Professor M. Louise Hull sub-specialties focus specifically on treatments for the following:

• Fertility
• Obstetrics & Reproductive Medicine
• Fertility and Conception
• Immunology and Infection

Education

• 2017 Certificate of Completion, Higher Education Academic Staff Leadership Colloquium Online, National Excellence in Educational leadership Iniative (NEELI)
• 2012 Graduate of the Australian Institute of Company Directors (GAICD)
• 2012 Certificate of Reproductive Endocrinology and Infertility (CREI), RANZCOG
• 2006 Fellowship of the Royal Australian and New Zealand College of Obstetricians and Gynaecologists (FRANZCOG)
• 2006 Doctor of Philosophy (PhD), St Edmunds College, University of Cambridge, UK
• 2000 Diploma of Fertility and Family Planning (DFFP) RCOG, UK
• 1999 Member of the Royal Australian and New Zealand College of Obstetricians and Gynaecologists (MRANZCOG)
• 1993 Diploma of Obstetrics (Dip Obs) University of Auckland, Auckland, NZ
• 1986 - 1991 Bachelor of Medicine and Surgery (MB ChB), Christchurch School of Medicine, University of Otago, New Zealand (8th in class, Distinction in Basic Sciences and Obstetrics and Gynaecology)
• 1983 - 1986 Bachelor of Science (BSc) (Double major in Biochemistry and Microbiology) University of Otago, New Zealand

Awards

• 2016 Paper of the Month, Robinson Research Institute
• 2015 Paper of the Month, Robinson Research Institute
• 2014 Award from Human Reproduction Update for being in the Top 10% of reviewers Award from Human Reproduction for being in the Top 10% of reviewers Invited member of the Faculty of 1000
• 2013 Invited International Ambassador for the World Endometriosis Society
• 2012 Awarded the Professor Derek Frewin AO Citation for Clinical Teaching
• 2009 Award for the best original scientific paper, Research Centre for Reproductive Medicine
• 2008 Award for best original scientific paper, Research Centre for Reproductive Medicine Award for best scientific paper, 10th World Congress of Endometriosis, Melbourne
• 2004 Burrough's Wellcome Travel Fellowship, Society for Gynaecological Investigation, Houston, USA
• 1998 Award for runner up best presentation, South West Obstetrics and Gynaecology Training Group, UK
• 1995 Immigrant Young Investigator Award, NZ Medical Women's Association Harvey Carey Memorial prize for best presentation, RNZCOG
• 1989 Distinction in Obstetrics and Gynaecology, MB.ChB, University of Otago, NZ
• 1988 Distinction in Basic Science and Clinical Science, MB.ChB, University of Otago, NZ

Directorships

• 2018-present:Member of the Governance committee, Jean Hailes, Australia
• 2016 - present: Board Member, Genea Oxford Women's Health Fertility, Christchurch, NZ
• 2016 - present: Board Member, FAB Software Ltd, Christchurch, NZ
• 2017 - present: Board Member, Endocrinology Today, Sydney Australia
• 2009 -Founding Member Fertility SA IVF Unit
• 2009 - 2011:Scientific Director, Fertility SA
• 2009 - 2012:Board Member, Fertility SA
• 2011 - present:New Developments Director

Membership of Societies

• Chair of the Written Examination Committee for CREI
• Endometriosis Awareness
• Invited Chair of the Implantation Special Interest Group
• Invited International Ambassador
• World Endometriosis Society
• Invited National Ambassador Endometriosis Awareness Member
• American Society of Reproductive Medicine (ASRM)
• Fertility Society of Australia (FSA)
• Society for Reproductive Biology (SRB), Australia
• Asia Pacific Endometriosis Alliance
• World Endometriosis Society
• Australian Gynaecological Endoscopic Society (AGES)
• Royal Australian and New Zealand College of Obstetricians and Gynaecologists (RANZCOG)

Professional Qualification

• 2014 - present: Associate Professor, Group Leader of the Endometriosis Research Group, Clinical Leader for the Fertility and Conception Theme, The Robinson Research Institute, Research Centre for Reproductive Health, University of Adelaide
• 2015 - present: Staff Specialist Gynaecologist, The Women's and Children's Hospital, Adelaide
• May 2009 - present: Consultant Fertility Specialist, Fertility SA, Adelaide

Publications

• V Nisenblat, DJ Sharkey, Z Wang, SF Evans, M Healey, EMC Ohlsson Teague, CG Print, SA Robertson, ML Hull. Plasma microRNAs display limited potential as diagnostic tools for endometriosis. J Clin Endocrinol Metab.2019,104(6):1999-2022.IF=5.44
• RJ Norman, H Alvino, ML Hull, BJ Mol, R Hart, TL Kelly, L Rombauts. Human growth hormone for poor responders: a randomised placebo-controlled trial shows no improved outcome for live birth. RBM Online. 2019, Pages 908-91
• MZ Johan,WV Ingman, SA Robertson, ML Hull.Macrophages infiltrating endometriosis-like lesions exhibit progressive phenotype changes in a heterologous mouse mode.J Reprod Immunol.2019 132:1-8 IF= 2.92
• Robertson, ES Green, AS Care, LM Moldenhauer, JR Prins, ML Hull, SC Barry, G Dekker. Therapeutic potential of regulatory T cells in preeclampsia - opportunities and challenges.Front Immunol.2019;10: 478 IF=6.43
• NP Johnson, S Baidya, SO Jessup, CG Print, A Muthukaruppan, LW Chamley, WE Hadden, ML Hull, AN Shelling, Randomised trial of lipiodol uterine bathing effect (LUBE) in women with endometriosis-related infertility.Fertility and Reproduction. 2019,1(1):57-64
• SF Evans, TA Brooks, AJ Esterman, ML Hull, PE Rolan. The co-morbidities of dysmenorrhea: A clinical survey comparing symptom profile in women with and without endometriosis. Journal of Pain Research 2018
• JE Schjenken, K Panir, SA Robertson and ML Hull.Exosome-mediated intracellular signalling impacts the development of endometriosis - new avenues for endometriosis research.Mol Hum Reprod 2018, 25 (1): 2-4. IF=3.449
• RJ Norman, H Alvino, ML Hull, BJ Mol, R Hart, TL Kelly, L Rombauts. Human growth hormone for poor responders: a randomised placebo controlled trial shows no improved outcome for live birth. Submitted Fertil Steril
• R Ehrlich, ML Hull, J Walkley, G Sacks. Intralipid immunotherapy for repeated IVF failure. Submitted JRI.
• MZ Johan,WV Ingman, SA Robertson, ML Hull. Longitudinal changes in macrophage phenotype during development of endometriosis-like lesions are regulated by transforming growth factor beta 1. Submitted J Reprod Imunol
• RD Rose, MF Barry, EV Dunstan, S Yuen, LP Cameron, EJ Knight, RJ Norman and ML Hull. The BlastGen pilot study: A prospective, pilot, randomised controlled trial of GM-CSF supplemented blastocyst media. Submitted Hum Reprod
• K Panir, J E Schjenken, SA Robertson, M L Hull. Non-coding RNA's in Endometriosis. Human Reproduction Update 2018.
• V Nisenblatt and ML Hull. Ovulation Induction: In Whom and how to use it. Endocrinology Today 2018, April p
• H Brown, E Green, T Tan, M Bermudez-Gonzalez, A Rumbold, ML Hull, RA Norman, N Packer, SA Robertson, J Thompson. Preconception onset diabetes is associated with embryopathy and fetal growth retardation, reproductive tract hyperglycosylation and impaired immune adaption to pregnancy. Scientific Reports. Accepted
• A Short and ML Hull. How to treat Paediatric and Adolescent Gynaecology. Australian Doctor 2017, 8 Dec : 17-24
• NP Johnson NP,L Hummelshoj , GD Adamson, J Keckstein, HS Taylor, MS Abrao,D Bush , L Kiesel, R Tamimi, KL Sharpe-Timms ,L Rombauts, LC Giudice, for the World Endometriosis Society Sao Paulo Consortium including M.L.Hull . World Endometriosis Society consensus on the classification of endometriosis. Hum Reprod. 2017; 32(2):315-324 (ISSN: 1460-2350) IF= 5.02 (CI=1)
• PAW Rogers, GD Adamson, M Al-Jefout, CM Becker, TM D'Hooghe, GAJ Dunselman, A Fazleabas, LC Giudice, AW Horne, ML Hull, Lone Hummelshoj, SAM, ScD, GW Montgomery, P Stratton, RN. Taylor, L Rombauts, PT Saunders, K Vincent, and KT. Zondervan for the WES/WERF Consortium for Research Priorities in Endometriosis. √جø¬ΩResearch priorities for endometriosis: recommendations from a global consortium of investigators in endometriosis', Reproductive Sciences, 2017, 24 (2): 202-226. IF =2.443 (CI=3)
• SA Robertson, M Jin, D Yu, LM Moldenhauer, M Davies, M L Hull, RJ Norman. Corticosteroid therapy in assisted reproduction - a faulty premise justifies immune suppression at conception, Human Reproduction, 2016, 31 (10): 2164. IF =4.569 (CI=6)
• V Nisenblat, ML Hull, PMN Boyssuyt, C Farquhar, N Johnson. Combination of tests for the non-invasive diagnosis of endometriosis. Cochrane Database of Systematic Reviews 2016, Issue 7 . Art. No.: CD012281. DOI: 10.1002/14651858.CD012281 IF=6.22 (CI=7)
• V Nisenblat, PMM Bossuyt, R Shaikh, C Farquhar, V Jordan, CS Scheffers, BWJ Mol, N Johnson, ML Hull. Blood biomarkers for the non-invasive diagnosis of endometriosis. Cochrane Database of Systematic Reviews 2016, Issue 5. Art. No.: CD01217 IF=6.22 (CI=12)
• D Gupta, ML Hull, I Fraser, L Miller, PMM Bossuyt, N Johnson, V Nisenblat. Endometrial biomarkers for the non-invasive diagnosis of endometriosis. Cochrane Database of Systematic Reviews 2016, Issue 4. Art. No.: CD012165. DOI:10.1002/14651858.CD012165 IF=6.22 (CI=5)
• V Nisenblat, PMN Bossuyt, C Farquhar, N Johnson, ML Hull. Imaging modalities for the non-invasive diagnosis of endometriosis. Cochrane Database of Systematic Reviews 2016, Issue 2. Art. No.: CD009591. DOI: 10.1002/14651858.CD009591.pub2 IF=6.22 (CI=20)
• LJ Moran, L Spencer, DL Russell, ML Hull, SA Robertson, TJ Varcoe, MJ Davies, HM Brown, RJ Rodgers and Robinson Research Institute Consortium of Fertility and Conception Practitioners. Research Priorities for Fertility and Conception Research as Identified by Multidisciplinary Health Care Practitioners and Researchers. Nutrients 2016, 8(1), 35; doi:10.3390/nu8010035 IF=3.79
• E Liu, V Nisenblat, C Farquhar, I Fraser, PMM Bossuyt, N Johnson, ML Hull. Urinary biomarkers for the non-invasive diagnosis of endometriosis. Cochrane Database of Systematic Reviews 2015, Issue 12. Art. No.: CD012019. DOI: 10.1002/14651858. CD012019 IF=6.22 (CI=8)
• JT McGuane, KM Watson, J Zhang, MZ Johan, Z Wang, G Kuo, DJ Sharkey, SA Robertson, ML Hull. Seminal Plasma Promotes Lesion Development in a Xenograft Model of Endometriosis. Am. J. Path, 2015;185(5):1409-1422 IF=4.602 (CI=2)
• T Pantasri, LL Wu, ML Hull, TR Sullivan, M Barry, RJ Norman, RL Robker. Distinct localisation of lipids in the ovarian follicular environment. Reprod, Fertil Develop, 2015;27(4):593-601 IF=2.135 (CI=4)
• CM Becker, MR Laufer, P Stratton, L Hummelshoj, SA Missmer, KT Zondervan, GD Adamson for the WERF EPHect Working Group including ML Hull, World Endometriosis Research Foundation Endometriosis Phenome and Bio banking Harmonisation Project: I. Surgical phenotype data collection in endometriosis research, Fertil Steril, 2014(11); 102(5): 1213-1222 IF=4.295 (CI=32)
• AF Vitonis, K Vincent, N Rahmioglu, A Fassbender, GM Buck Louis, L Hummelshoj, LC Giudice, P Stratton, D Adamson, CM Becker, KT Zondervan, SA Missmer for the WERF EPHect Working Group including ML Hull, World Endometriosis Research Foundation Endometriosis Phenome and bio banking harmonization project: II. Clinical and covariate phenotype data collection in endometriosis research, Fertil Steril, 2014(11); 102(5): 1223-1232 IF=4.295 (CI=29)
• N Rahmioglu, A Fassbender, AF Vitonis, SS Tworoger, L Hummelshoj, TM D'Hooghe, GD Adamson, LC Giudice, CM Becker, KT Zondervan, SA Missmer and WERF EPHect Working Group including ML Hull, World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonization Project: III. Fluid bio specimen collection, processing, and storage in endometriosis research, Fertil Steril, 2014 (11); 102(5): 1233-1243 IF=4.295 (CI=26)
• A Fassbender, N Rahmioglu, AF Vitonis, P Vigano, LC Giudice, TM D'Hooghe, L Hummelshoj, GD Adamson, CM Becker, SA Missmer, KT Zondervan for the WERF EPHect Working Group including ML Hull, World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonisation Project: IV. Tissue collection, processing and storage in endometriosis research. Fertil Steril, 2014 (11); 102(5): 1244-1253 IF=4.295 (CI=29)
• ML Hull and V Nisenblat, Tissue and circulating microRNAs influence reproductive function in endometrial disease. RBMonline 2013,27, 5, 515-29 IF=2.9) (CI=26) H Nakamura, MJ Jasper, ML Hull, JD Aplin, SA Robertson. Macrophages regulate expression of ?1, 2 fucosyltransferase genes in human endometrial epithelial cells through LIF signalling. Mol Hum Reprod 2012, 18, 4, 204- 215. IF=3.506 (CI=16)
• ML Hull, MZ Johan, WH Hodge, SA Robertson, WV Ingman. Host-derived TGFB1 deficiency suppresses lesion development in a mouse model of endometriosis. Am J Path 2012, 180, 3, 880-887 IF=5.224 (CI= 24)
• Z Zhao, L Croft, DR Nyholt, B Chapman, SA Treloar, ML Hull, GW Montgomery. Evaluation of polymorphisms in predicted target sites for micro-RNAs differentially expressed in endometriosis. Mol Hum Reprod, 2011, 17(2), 92-103 IF=3.506 (CI=21)
• EM Ohlsson Teague, CG Print, ML Hull. The role of microRNAs in endometriosis and associated reproductive conditions. Hum Reprod Update 2010, 16(2):142-65 IF=8.65 (CI=70) ML Hull, D Nemeth, WM Hague, C Wilkinson, J Liebelt, M Lane, D Feil. Mitochondrial fatty acid transport enzyme deficiency - implications for IVF. Fertil Steril 2009, 91(6) 2732, 11-14. IF=4.167. (CI=2)
• EMC Ohlsson Teague, KH Van der Hoek, MB Van der Hoek, N Perry, P Wagaarachichi, SA Robertson, CG Print, ML Hull. MicroRNA-regulated pathways associated with endometriosis. Mol Endocrinol, 2009, 23(2): 265√جø¬Ω275. IF=5.337 (CI=167)
• ML Hull, C Range-Escareno, JM Godsland, JR Doig, C. M. Johnson, SC Phillips, SK Smith , S Tavar√جø¬Ω, CG Print, DS Charnock-Jones. Endometrial-peritoneal interactions during endometriotic lesion establishment. Am J Path 2008, 173 (3): 700-715 IF=5.487 (CI=69)
• ML Hull, MT Gun, M Ritossa. Hook-wire insertion facilitates the excision of scar endometriosis. BJOG. 2006 113: 774-776. IF=3.86 (CI=1)
• ML. Hull and DS. Charnock-Jones Is the dose to inhibit the COX-2 enzyme in nude mice also adequate in human endometrial tissues? Human Reprod 2005 20 (9): 2665-2666. IF=3.365 (CI=1)
• ML Hull, A. Prentice, DY Wang, SK Smith, DS Charnock-Jones. COX-2 inhibition does not reduce lesion size or number in a nude mouse model of endometriosis. Hum Reprod 2005, 20 (2): 350-358. IF=3.365 (CI=41)
• ML Hull, DS Charnock-Jones, CLK Chan, KL Bruner-Tran, KG Osteen, BDM Tom, TPD Fan, SK Smith. Anti-angiogenic agents are effective inhibitors of endometriosis. JCEM 2003, 88 (6):2889-2997. IF=6.31 (CI=199)
• JM Borthwick, DS Charnock-Jones, BD Tom, ML Hull, R Tierney, SC Phillips, SK Smith. Determination of the transcript profile of human endometrium. Mol. Hum. Reprod. 2003, 9 (1):19-33. IF=3.48 (CI=238)
• WJ Inder, TC Prickett, MJ Ellis, ML Hull, RA Reid, PS Benny, JA Livesey, RA Donald. The utility of plasma CRH as a predictor of preterm delivery. JCEM 2000, 86 (12):5706-5710. IF=5.447 (C =51)
• ML Hull, JJ Evans, JS Livesey, PS Benny. The effect of recombinant follicle stimulating hormone (Gonal-F) on endogenous luteinising hormone secretion in women. Hum. Reprod. 1998, 13: 1139-1143. IF=4.58 (CI=7)
• ML Hull, RA Reid, JJ Evans, PS Benny, DR Aitkin. Pre-ovulatory administration of oxytocin promotes the onset of the luteinising hormone surge in human females. Hum. Reprod. 1995, 10: 2266-2269. IF=4.58 (CI=26)

University of Adelaide

2005 - 2016 - Leader of the Endometriosis Group

• Employed 3 post-doctoral Fellows
• Employed 1 Research Assistant
• Developed projects and national and international collaborations
• Applied for grants and managed budgets
• Obtained Animal and Human Ethics approvals
• Reported to grant committees and commercial funding bodies
• Oversaw Occupational Health and Safety processes
• Interview Committee for Bioinformatics position
• Member of the Fertility & Conception Theme Steering Group

Research Projects

Principal Investigator

• MicroRNA deficient mouse models of endometriosis
• Tissue remodelling in endometriosis
• MicroRNAs in endometriotic lesions
• Ectopic endometrial lesions in a TGFB1 deficient mouse model
• Endometriosis-associated microRNAs in serum
• The diagnostic potential of serum microRNAs in endometriosis
• Macrophage activity in developing endometriosis lesions
• Bone remodelling proteins in endometriosis
• MicroRNA activity in endometriotic lesions
• The effect of seminal plasma on ectopic endometrial lesion development in a mouse model
• Endometriosis like lesion development in microRNA deficient mouse models
• Cochrane Review: Diagnostic tests in endometriosis: imaging, endometrium, blood, urine and combined

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